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  IBSA Educational Program
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Friday, May 31, 2013

Striving for Excellence: The IBSA Educational Program
The program at the BCGIP-COGI meeting will discuss the physiology and pathophysiology of the luteal phase in the various types of ART and the need for hormone support in stimulated cycles.
 
Program Title: A PROPER APPROACH TO LUTEAL PHASE SUPPORT: A KEY TO SUCCESS
Capsule: Ovarian stimulation results in supraphysiological steroid concentrations along with low LH levels during the luteal phase, approximately 8-9 days after hCG administration. This results in decreased corpus luteum production of estrogen and progesterone, which is associated with decrease probability of successful implantation and ongoing pregnancy.The triggering of the final stages of ovulation using either hCG (5,000-10,00IU) or GnRH-a induce specific, yet different adverse consequences on the luteal phase that call for corrective measures.
The program developed below was built to raise the controversies on the subject, striving to reach a consensus regarding lutal support in ART cycles.

Part 1
Basic understanding of the luteal phase support (LPS) in ART treatment cycles
Is there a dose relationship in the endometrial effects of progesterone?
Dominique De Ziegler, France
Why do we need additional progesterone when endogenous levels are so high?
Pedro Barri, Spain
PANEL DISCUSSION
Should LPS be adjusted to the COS protocol?
Milton Leong, Hong Kong
What about ovulation induction cycles?
Salim Daya, Canada
Which formulation should we use?
Roy Homburg, Israel
Which is the optimal duration of LPS in pregnancy? Science vs. clinical experience
Zeev Shoham, Israel
Is there a place for IM progesterone supplementation?
Sherman Silber, USA
Discussion
 

Part 2
How do we choose the treatment?
Luteal support: Is there a place for new/old formulation?
Salim Daya, Canada
Latest results from IVF worldwide survey
Zeev Shoham, Israel
The luteal phase following GnRH agonist ovulation triggering
Seang Lin Tan, Canada
PANEL DISCUSSION
Is there a risk involved in additional or high dose progesterone during the luteal phase or early pregnancy?
Dominique De Ziegler, France
Is there a role for gonadotropin releasing hormone (GnRH)-agonists as a luteal supplement in GnRH- agonist and antagonist stimulated cycles?
Pedro Barri, Spain
Active management of the luteal phase
Seang Lin Tan, Canada
Premature bleeding: how to approach it?
Klaus Diedrich, Germany
What is the effect of progesterone on recurrent miscarriage, if any?
Salim Daya, Canada
Should hCG be added to all supplemented protocols?
Gedis Grudzinskas, UK
Is there a need for additional estrogen supplementation?
Ariel Weissman, Israel
Discussion

 


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